Events
Maintaining Genomic Health in a Changing World
TwinStrand Biosciences is a Diamond sponsor at the 13th International Conference on Environmental Mutagens
Workshop 4: Advancing the Next Generation of Genetic Toxicology and Cancer Risk Assessment
Saturday, August 27th | 7:30 am – 3:30 pm ET | Ontario – Level 3
Chief Scientific Officer, and Founder Jesse Salk will be presenting an Overview of Error Corrected Sequencing (ecNGS) technologies alongside nine compelling presentations on the use of ecNGS methods.
Symposium-1: Advancing Mechanistic Analyses in Genetic Toxicology Using High-Content and High-Throughout Methodologies
Sunday, August 28th | 10:30 am – 12:30 pm ET | Confederation I – Level 4
TwinStrand is a sponsor of this symposium which examines the advantages of high-throughput and high-content assays for the detection of genetic damage and explores the regulatory and mechanistic applications of data generated using such approaches. Learn how regulatory genetic toxicology screening is being modernized by innovative tools and techniques.
Maintaining Genomic Health in a Changing World
TwinStrand Biosciences is a Diamond sponsor at the 13th International Conference on Environmental Mutagens
TwinStrand Biosciences is a gold sponsor at the 2022 Annual Meeting
Gold Sponsor Industry Showcases: Monday, August 1st at 3:23pm CST
Exhibit Hall: Booth #22
TwinStrand Biosciences will be the gold sponsor at the 2022 Annual Meeting at the Royal Hall in Harrogate
TwinStrand Biosciences, in collaboration with the UKEMS (United Kingdom Environmental Mutagen Society), is hosting a Next Generation Sequencing Workshop on Thursday, May 12th at 1 Wimpole Street, London.
Poster Presentation by Zach Norgaard
Thursday, May 5th, 2022 – 5:45pm – 7:15pm PST
Ultra-Sensitive Duplex Sequencing for Quantifying Multi-Individual Cell Therapy Sub-Population Fractions
CEO Jesse Salk MD, PhD will be speaking at the Life Sciences Innovation Northwest (LSINW) 2022 Convention during the Research Tools & Medical Device session.
Wednesday, April 20th, 2022 – 2:46pm PST
Poster Presentation by Jake Higgins, PhD
Monday, April 11th, 2022 – 9:00am – 12:30pm CDT
Duplex Sequencing reveals ubiquitous clonal hematopoiesis and complex
donor-recipient clonal dynamics following hematopoietic stem cell transplant
Bronze Sponsorship Talk presented by CEO Jesse Salk, MD, PhD
Wednesday, March 3, 2021 – 2:45pm – 3:00pm EST
Ultra-Sensitive Duplex Sequencing for Tracking of Allogeneic Cell Therapies
Poster Presentation by Jake Higgins, PhD
December 6, 2020 – 7:00 am – 3:30 pm PST
Duplex Sequencing with Patient-Specific Hybrid Capture Panels Reveals Ultra-Low Frequency Measurable Residual Disease in Pediatric Acute Myeloid Leukemia
Webinar Presentation by CEO Jesse Salk, MD, PhD
November 30, 2020 – 2:00 pm GMT (6:00 am PST)
Presentation by Jake Higgins, PhD
Rapid, High Precision Identification of Relative Sensitivity of Different Resistance Mutations to TKI Therapies using In Vitro Competition and Ultra-Accurate Duplex Sequencing
Presentations and Posters featuring TwinStrand Duplex Sequencing™ Technology
- Adapting Next-Generation Genetic Toxicology Endpoints to the Human In Vitro Air-Liquid-Interface Airway Tissue Model, Yiying Wang, FDA/NCTR
- Adopting Duplex Sequencing Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)- Exposed Rats, Stephanie Smith-Roe, National Toxicology Program
- Comparison of Duplex Sequencing and CarcSeq Error-Corrected NGS methods for Detection of Preneoplastic Clonal Expansions in Normal, Healthy Human Tissues, Meagan Myers, PhD, DHHS/FDA/NCTR
- Duplex Sequencing™ Demonstrates Dose-related Increases in Mutation Frequencies and C>A Transitions in the Bone Marrow of MutaMouse Males Exposed to Benzo(a)pyrene. LeBlanc, D. et al.
- Error-Corrected Duplex Sequencing; Bioinformatic Challenges, Clint Valentine, TwinStrand
- Extension of Error-Corrected Duplex Sequencing to Structural Variant Detection, Thomas E. Wilson, MD, PhD, University of Michigan Medical School
- Interspecies Comparison of Chemical-induced Mutagenesis by Duplex Sequencing, Bob Young, Millipore-Sigma
- Ultra-Deep Sequencing of Blood and Urine to Test for Exposure to Aristolochic Acids, Arnoud Boot, Duke-NUS Medical School
Virtual Presentation by CEO Jesse Salk, MD, PhD
“Ultrasensitive Genetic Detection: Below One-In-One-Million”
TwinStrand is a science-first genomics company based around Duplex Sequencing, an ultra-sensitive DNA analysis technology designed to improve cancer diagnostics. We use a combination of specialized biochemistry and powerful cloud-based computation to improve the accuracy of existing DNA sequencers by more than 10,000-fold. This unprecedented resolution lets us solve a variety of clinically actionable oncologic ‘needle in a haystack’ problems such as early detection of cancer, monitoring for residual tumor cells after therapy and identification of new chemicals and environmental exposures that put people at risk for cancer. We make it possible for researchers to see faint signals that were previously hidden, to help our collective effort to reduce global burden of cancer.
Presentation by CEO Jesse Salk, MD, PhD
Ultra-Sensitive Residual Leukemia Detection with Patient-Specific Duplex Sequencing
View Talk
Poster Presented
Super CHIP: Duplex Sequencing Reveals Clonal Dynamics in Blood that are Magnitudes more Complex than Previously Recognized
View Poster
Presentation by CEO Jesse Salk, MD, PhD
Ultrasensitive Minimal Residual Disease Detection By Duplex Sequencing
Abstract
Duplex Sequencing enables an unprecedented level of NGS accuracy, with error rates below one-in-ten-million. The technology is ideally suited to detection of residual cancer (MRD), where lingering tumor cells are vastly outnumbered by normal cells. Here we present Duplex Sequencing-based MRD data from three clinical studies in acute myeloid leukemia.
Presentation by Jake Higgins
Clonal Landscapes of Hematologic Malignancies Redefined by Ultra-Sensitive Duplex Sequencing
View Poster Presented at Event
Presentation by CEO Jesse Salk, MD, PhD
Genetic susceptibility and biologic markers of carcinogen exposure
