TwinStrand DuplexSeq measuring MRD in AML

Enhancing the Accuracy of Next-Generation Sequencing for Detecting Rare and Subclonal Mutations

Next-generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of ∼1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but […]